In general a "Run" is a single run such as "Mr. K". A "Run Sequence" is a sequence of runs, such as "Fast Lane > Black & Blue".
Any of the plots / stats about "Main Runs" only considers run sequences that have at least one * on them; the denominator is the total number of such sequences.
Any of the plots / stats about "All Runs" considers all run sequences; the denominator is the total number of run sequences.